MICROSPHERES: A NOVAL APPROACH FOR DRUG DELIVERY SYSTEMS

Abstract

Microspheres constitute an important part of drug delivery system by virtue of there small size and efficient carrier characteristics. Microspheres in general have to the potential to be used for targeted and control released drug delivery: by coupling of mucoadhesive, oral, floating etc properties of microspheres. Novel drug delivery systems have several advantages over conventional multi dose therapy. Much research effort in developing novel drug delivery system has been focused on controlled release and sustained release dosage forms. Now considerable efforts are being made to deliver the drug in such a manner so as to get optimum benefits. There are various approaches in delivering a therapeutic substance to the target site in drug delivery systems. Microspheres are potential candidates for the protein drug delivery. These systems such as biodegradable microspheres are capable of delivering drugs over longer time periods than conventional formulations. Microspheres received much attention not only for prolonged release, but also for targeting of anticancer drugs to the tumor. The intent of the paper is to highlight method of preparation and novel drug delivery systems for microspheres.