DRUGS RESISTANCE AND SCREENING OF ANTIBACTERIAL ACTIVITIES OF PHYLLANTHUS EMBLICA (L) FRUITS PRESERVING PROTIENS

Abstract

The fruit of Emblica officinalis commonly known as amla is highly valued in traditional Indian medicine. Phyllanthus emblica (L) has been used for the anti-inflammatory and anti-pyretic treatments by the rural population. P. emblica has been used for the treatment of several. Based on the traditional knowledge about the plant, present study was conducted. To evaluate the scientific basis for the use of plant, the antimicrobial activities of the extracts at different doses (10mg and 20mg/ml) of the leaves and fruits were evaluated against some common pathogenic bacteria using agar disc diffusion method. Gram positive bacteria like staphylococcus aureus and Bacillus subtilis gram negative bacteria like Pseudomonas aeruginosa, and Escherichia coli were used and antimicrobial activity of the concentrated extracts was evaluated by the diameter zone of inhibition against the above microorganisms. Plant extracts were active against both gram positive, gram negative Bacteria. The above observation indicates that, P. emblica has broad spectrum antibacterial activity and a potential source of new classes of antibiotics that could be useful for infectious disease chemotherapy and control. The study also conducted on the isolation of the chemical constituents present in the plant.