SIMULTANEOUS ESTIMATION OF ASPIRIN AND ROSUVASTATIN CALCIUM IN COMBINED DOSAGE FORM USING DERIVATIVE SPECTROPHOTOMETRIC METHOD

  • Manish j. Patel Department of Quality Assurance, Arihant School of Pharmacy and Bio-research Institute, Adalaj, DistGandhinagar, Gujarat, India.
  • Dr. Hiral j. Panchal Department of Quality Assurance, Arihant School of Pharmacy and Bio-research Institute, Adalaj, DistGandhinagar, Gujarat, India.
Keywords: First order derivative spectroscopy, Aspirin (ASP), Rosuvastatin Calcium (ROS)

Abstract

A simple and reproducible spectrophotometric method, requiring no prior separation, has been developed for the estimation of Aspirin and Rosuvastatin Calcium in combined dosage form. First order derivative spectroscopy method was adopted to eliminate spectral interference, using 255.50 nm and 288.50 nm as zero crossing points for Aspirin and Rosuvastatin Calcium respectively. Methanol was used as a solvent. The results of analysis have been validated statistically and recovery studies confirmed the accuracy of the proposed method.
How to Cite
Manish j. Patel, & Dr. Hiral j. Panchal. (1). SIMULTANEOUS ESTIMATION OF ASPIRIN AND ROSUVASTATIN CALCIUM IN COMBINED DOSAGE FORM USING DERIVATIVE SPECTROPHOTOMETRIC METHOD. International Journal of Pharma Professional’s Research (IJPPR), 3(1), 456-461. Retrieved from https://ijppronline.com/index.php/IJPPR/article/view/88
Issue
Vol 3 No 1 (2012): January Issue-1
Section
Articles