International Journal of Pharma Professional’s Research (IJPPR)

In-vitro Antidiabetic Activity of Acacia Arabica Leaves

Authors

  • Vineet Kumar

    School of Pharmacy, Monad University, Hapur, U.P., India.
    Author
  • Tabassum Saifi

    Monad University, N.H. 9, Delhi Hapur Road
    Author
  • Shipra

    Monad University, N.H. 9, Delhi Hapur Road
    Author
  • Anil Kumar

    Monad University, N.H. 9, Delhi Hapur Road
    Author
  • Bhanoo Pratap Singh

    Monad University, N.H. 9, Delhi Hapur Road
    Author

DOI:

https://doi.org/10.69580/rdh1w986

Keywords:

Diabetes mellitus, antidiabetic, antioxidant, Acacia Arabica, acarbose

Abstract

The aim of the present study was to investigate the phytochemical bioactive compounds of the ethanolic extract of Acacia Arabica leaves and its in-vitro anti-diabetic activity. The intestinal digestive enzymes alpha-glucosidase and alpha-amylase play a very important role in the digestion of carbohydrates. One antidiabetic therapeutic approach reduces the post-prandial glucose level in blood by the inhibition of alpha-glucosidase and alpha-amylase enzymes. These are important strategies in the management of blood glucose. The results of this assay suggest that the presence of bioactive compounds could be responsible for the versatile medicinal properties of this plant including diabetes, the extract exhibits a dose-dependent increase in inhibitory effect on glucose diffusion (up to 72.03%), and alpha-amylase enzyme (up to 64.84%). The current in-vitro study proves that the ethanolic extract of Acacia Arabica leaves has anti-diabetic activity.

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Published

30-10-2023