In-vitro Antidiabetic Activity of Xanthium strumarium L. Leaves

Abstract

Diabetes mellitus has become a major public health and economic problem across the globe. The inadequacies, as well as serious adverse effects associated with conventional medicines, led to a determined search for alternative natural therapeutic agents. This study aimed to evaluate the in-vitro antidiabetic effects of Xanthium Strumarium L. Leaves Extracts. The % yield of acetone and ethyl acetate extract was found to be 1.9% and 2.5% respectively. Qualitative phytochemical tests confirmed the presence of alkaloids, glycosides, saponins, fats and oils, and phenols in acetone extract while alkaloids, glycosides, glycosides, saponins, steroids and phenols were present in ethyl acetate extract. The in-vitro antidiabetic and antioxidant studies of the extract revealed that the ethyl acetate extract of Xanthium strumarium L. leaves showed good antidiabetic and antioxidant potential when compared with acetone extract and significant with standard compound Acarbose.