An overview of Quinazolines: Applicability of molecular docking in Cancer therapy

Abstract

Medicinal chemistry is distracted with the elaboration, discovery, confirmation of physical and chemical approaches, and the synthesis in laboratory. Quinazoline derivatives occupy crucial positions in modern medicinal chemistry and possess established application as medicine. Several researches have been accomplished on derivatives of the quinazoline for different many pharmacological activity are reported recently. The most important process molecular docking modification is the preliminary step in the drug designing of novel drugs. The main aim of this review is to quiz or examine recently molecular docking strategies used in medicinal chemistry and in the drug discovery, Investigating the advancement in the field of computer aided drug design, and important role play through the ligand-based method. The drug discovery and the field of CADD is fast flourishing area that has seen various successes. Several giant pharmaceutical industries, in additionally to academia, adopt computeraided drug design and discovery for drug lead discovery.