CHEMISTRY AND SIGNIFICANCE OF CHEMOPREVENTIVE NUTRACEUTICALS: A REVIEW

Mahendra Dwivedi; Rohit Kumar; Shloke Kumar Dwivedi; Ankush Sachan

Mahendra Dwivedi RKDF School of Pharmaceutical Science, Bhopal, Madhya Pradesh,
Rohit Kumar BMS College of Pharmacy, Tiloi, Amethi, Uttar Pradesh
Shloke Kumar Dwivedi BMS College of Pharmacy, Tiloi, Amethi, Uttar Pradesh
Ankush Sachan BMS College of Pharmacy, Tiloi, Amethi, Uttar Pradesh

Keywords: Nutraceutical, Chemotherapy, Chemoprevention, Antitumor, Cancer

Abstract

Nutraceutical is a food or part of food that has physiological and medical benefit and is used in the prevention of various diseases. Cancer is a serious health issue and is rarely curable that depend on its type and site. For the treatment of cancer different therapies like chemotherapy, radiotherapy, hormone therapy are used, but major disadvantage of these therapies are that they have many side effects including gastrointestinal problems, changes in skin and hair loss. According to new research, some nutraceuticals may influence the cellular and molecular steps that contribute to cancer development. Studies suggest that combination therapy can help in cancer prevention much better than a single nutraceutical. Combination strategies to chemo prevention can take various forms: two or more phytochemicals, a chemically synthesized phytochemical and an efficient drug or a chemically synthesized phytochemical and a natural nutrient. The aim of this chapter is to analyze the chemo preventive significance of the nutraceuticals.