CURRENT APPROACHES IN TARGETING CANCEROUS CELLS AND NOVEL ANTICANCER DRUG DESIGNING

  • Sahil Kumar School of Pharmacy and Emerging Sciences, Baddi University of Emerging Sciences & Technology, Baddi, Distt. Solan (H.P.), India
  • Sachin Goyal LLR College of Pharmacy, Moga (Punjab), India
  • Minky Mukhija Ch. Devi Lal College of Pharmacy, Jagadhri, Yamunanagar (Haryana), India 135003
  • Rakesh K. Sindhu Chitkara College of Pharmacy, Chitkara University, Rajpura, Patiala, Punjab, India
Keywords: Cancer, DNA, anticancer drugs

Abstract

This review describes the current approaches in targeting cancerous cells and novel anticancer drug designing highlighting the identification and characterization of the biologically important lesions produced on DNA by important DNA-reactive drugs, molecular strategies to improve the sequence selectivity of existing groups of DNA-reactive drugs. The design of mechanism-based screens to identify new classes of drugs that react with DNA and associated targets the design of new drug classes based upon the identification of pharmacologically selective receptors on, or associated with DNA have also been described.
How to Cite
Sahil Kumar, Sachin Goyal, Minky Mukhija, & Rakesh K. Sindhu. (1). CURRENT APPROACHES IN TARGETING CANCEROUS CELLS AND NOVEL ANTICANCER DRUG DESIGNING. International Journal of Pharma Professional’s Research (IJPPR), 7(2), 1-15. Retrieved from https://ijppronline.com/index.php/IJPPR/article/view/183
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Articles