IN-VITRO STUDIES AND CHARACTERIZATION OF SOLID LIPID NANOPARTICLES OF PROTEASE INHIBITOR, ATAZANAVIR

  • Balvinder Singh Professor, Department of Pharmacology, Baba Mastnath University, Asthal Bohar, Rohtak-124001
  • Anupama Diwan Professor and Programme Director, School of Pharmaceutical Sciences, Apeejay Stya University, Gurgaon, Haryana, India.
Keywords: Protease Inhibitors, Atazanavir, Solid Lipid Nanoparticles, Entrapment Efficacy, Drug Loading, Particle size, Drug Release, TEM imaging, diffusion studies using dialysis membrane

Abstract

Protease Inhibitors are the new class of anti-HIV agent. Protease Inhibitors, e.g. Atazanavir, important constituents of the Highly Active Antiretroviral Therapy regimen, have dramatically impacted outcome of HIV treatment. In this research study, the Solid Lipid Nanoparticles of Protease Inhibitor, Atazanavir was characterized by entrapment efficacy, drug loading, particle size, zeta potential and drug release.
How to Cite
Balvinder Singh, & Anupama Diwan. (1). IN-VITRO STUDIES AND CHARACTERIZATION OF SOLID LIPID NANOPARTICLES OF PROTEASE INHIBITOR, ATAZANAVIR. International Journal of Pharma Professional’s Research (IJPPR), 3(3), 597-608. Retrieved from https://ijppronline.com/index.php/IJPPR/article/view/109
Issue
Vol 3 No 3 (2012): July Issue-3
Section
Articles