A REVIEW: PHARMACOKINETICS APPLICATION OF FLOUROQUINOLONS

  • Gupta Ritu Department of pharmacy, B.I.T. Meerut, India
  • Sharma K. K Department of pharmacy, B.I.T. Meerut, India
  • Sharma R D Department of pharmacy, B.I.T. Meerut, India
  • Tyagi Sachin Department of pharmacy, B.I.T. Meerut, India
  • Yadav B.P. Department of Chemistry, Meerut college Meerut, India
Keywords: Fluoroquinolones; Pharmacokinetics; Resistance; Therapeutic use

Abstract

This review outlines some of pharmacokinetic parameters factors of fluoroquinolones antimicrobial agents. The oral absorption is not altered in human patients with disease. Plasma protein binding of the quinolones varies but newer quinolones less bound to plasma proteins. The serum concentration peak is reached rapidly. Most of the fluoroquinolone primary metabolites are active against bacteria: however, these metabolites have a shorter elimination half-life than their parent compound.
How to Cite
Gupta Ritu, Sharma K. K, Sharma R D, Tyagi Sachin, & Yadav B.P. (1). A REVIEW: PHARMACOKINETICS APPLICATION OF FLOUROQUINOLONS. International Journal of Pharma Professional’s Research (IJPPR), 3(2), 561-571. Retrieved from https://ijppronline.com/index.php/IJPPR/article/view/102
Issue
Vol 3 No 2 (2012): April Issue-2
Section
Articles