Cancer: A New Era for cancer prevention

Ritu Gupta; Dr. Firoz Anwar; Dr. K.K. Sharma; Dinesh Kr. Gupta; R.D. Sharma; Sachin tyagi

Ritu Gupta School of Pharmacy, Bharat Institute of technology, Meerut, 250103
Dr. Firoz Anwar Department of Phrmacy, Siddhartha Institute of Pharmacy, Dehradun
Dr. K.K. Sharma School of Pharmacy, Bharat Institute of technology, Meerut, 250103
Dinesh Kr. Gupta School of Pharmacy, Bharat Institute of technology, Meerut, 250103
R.D. Sharma School of Pharmacy, Bharat Institute of technology, Meerut, 250103
Sachin tyagi .School of Pharmacy, Bharat Institute of technology, Meerut, 250103

Keywords: - COX, Cancer Stem Cells, DNA damage repair mechanism, Mcl-2

Abstract

We are currently on the brink of a new era in the understanding, detection, diagnosis and treatment of cancer. Drawing on new findings from diverse areas of research – ranging from cell biology, to biophysics, to epigenomics – the current thinking about the origins of cancer is undergoing a revolution, driven by technical and methodological advances. In this review we discuss recent progress made in cancer research work and hypothesis in prevention of cancer. Accumulating evidence has implicated that development of NF-ĸB targeted gene therapy and the evolution towards clinical application and cyclooxygenase (COX-2) inhibitor i.e. nonsteroidal anti-inflammatory drugs (NSAIDs) prevent colon and possibly other cancers has spurred novel approaches to cancer prevention. DNA Damage Repair and Response Proteins as Targets for Cancer Therapy, Cancer Stem Cells, Role of chelates in treatment of cancer and Mcl-1 plays a critical pro-survival role in the development and maintenance of both normal and malignant tissues, as well as use of peptides in cancer treatments.