Medicinal and therapeutic properties of Jamun (Syzygium cumini) – A Comprehensive Review

Akram Choudhary; Md. Noman; Uzma Bano; Asim A Khan; Jamal Akhtar; Showkat R. Mir; M. Shahar Yar

Akram Choudhary Department of Pharmaceutical Chemistry, School of Pharmaceutical Education and Research (SPER), Jamia Hamdard, India
Md. Noman Department of Pharmaceutical Chemistry, School of Pharmaceutical Education and Research (SPER), Jamia Hamdard, India
Uzma Bano School of Unani Medical Education and Research (SUMER), Jamia Hamdard, India
Asim A Khan Central Council for Research in Unani Medicine, Ministry of AYUSH, Government of India
Jamal Akhtar Central Council for Research in Unani Medicine, Ministry of AYUSH, Government of India
Showkat R. Mir Department of Pharmaceutical Chemistry, School of Pharmaceutical Education and Research (SPER), Jamia Hamdard, India
M. Shahar Yar Department of Pharmaceutical Chemistry, School of Pharmaceutical Education and Research (SPER), Jamia Hamdard, India

Keywords: Hepatocellular carcinoma, Anti-oxidant, Jamun, Traditional Unani medicine, Active constituent.

Abstract

Hepatocellular carcinoma (HCC) is the seventh most common cancer and the third leading cause of cancer-related death globally. It has a poor prognosis and is resistant to the majority of chemotherapeutics. The present review aimed to highlight studies into the tumor cycle and its prevention by appropriate herbal (Ayurvedic/Unani) medicine that is essential to reduce the effects of the deadly disease. There are few treatment options for endstage liver cancer, which forces patients to undergo expensive liver transplantation, which is not an option in the majority of nations. Herbal medicine has experienced exponential growth in recent years, and due to its natural origins and limited side effects, these medications are becoming more and more popular in both developed and developing nations. The antidiabetic function of S. cumini has the most potential nutraceutical value among these advantageous physiological effects. The numerous phytoconstituents included in the fruit, including tannins, alkaloids, steroids, flavonoids, terpenoids, fatty acids, phenols, minerals, carbohydrates, and vitamins, are primarily responsible for S. cumini's favourable benefits on health. An overview of the scientific data supporting S. cumini's pharmacological potential is provided in this review.