Formulation and Evaluation of tablet of a Classical Fermented Preparation of Dashmularishta

Abstract

Dashmularishta is a fermented liquid preparation made with the various ingredients in the formulation composition. It is rejuvenator and revitalizer and commonly known as restorative tonic. It relives post delivery weakness. It contains not more than 10%, and not less than 5% of alcohol that is self generated in the preparation over a period of time. This syrup promotes vitality and strength. It improves milk production in women’s. This is very useful in menopause. Dashmularishta restores energy in women after delivery. This is a tonic made from different herbs. It helps in removing toxins from body and nourishes body tissues. It maintains healthy female reproductive system. It is also a curative for general weakness. It combines synergistic benefit of Dashmool with other herbs. The present study involved the preparation of conventional tablet of Dashmularishta. Decoction of all the herbs was prepared in the boiler. Decoction was concentrated by use of falling film evaporator. Powder from the concentrated decoction was prepared by Spray drier. Tablets were prepared by direct compression. Dashmularishta tablets each weighing 475 mg containing 325 mg of drug was formulated. Lubricated blends were characterized for physical properties like loose bulk density, tapped density, angle of repose, Carr’s index, Hausner´s ratio; all blends showed satisfactory properties. Tablets were evaluated for uniformity of weight, thickness, hardness, percentage (%) friability and in vitro release studies.